SCHEMBL6764255

SCHEMBL6764255

CCCCOc1cn(Cc2ccccc2)c(=O)o1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.45
HPGD P15428 1/20 0.43
TLR7 Q9NYK1 1/20 0.42
ALDH1A1 P00352 2/20 0.41
TSHR P16473 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPK14 Q16539 1/20 0.39
PDE4A P27815 2/20 0.38
PDE4B Q07343 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
PDE3B Q13370 1/20 0.38
PDE3A Q14432 1/20 0.38
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6761320 0.93 HPGD (0.44) TP53HPGDALDH1A1TSHRMEN1
SCHEMBL6759650 0.87 HPGD (0.47) HPGDALDH1A1MEN1KMT2AMAPK14
SCHEMBL6757710 0.82 MAPK14 (0.49) HPGDALDH1A1MEN1KMT2AMAPK14
SCHEMBL4680991 0.81 HPGD (0.49) HPGDALDH1A1MEN1KMT2AMAPK14
SCHEMBL6757705 0.77 HPGD (0.46) TP53HPGDMEN1KMT2APDE4A
SCHEMBL6764108 0.77 MEN1 (0.48) HPGDMEN1KMT2AMAPK14FAAH
SCHEMBL6759698 0.73 MET (0.39) TP53ALDH1A1TSHRL3MBTL1MEN1
SCHEMBL22252624 0.72 HPGD (0.49) TP53HPGDALDH1A1L3MBTL1MEN1
SCHEMBL8725302 0.71 ASAH1 (0.46) HPGDALDH1A1L3MBTL1FAAHMGLL
SCHEMBL14470357 0.70 MAPK14 (0.51) ALDH1A1MEN1KMT2ATDP1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723860-B2 7a-alkoxy-4H-pyrano[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2004-04-20 US disclosed
EP-1207162-B1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same UBE INDUSTRIES (JP) 2004-02-25 EP disclosed
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same UBE INDUSTRIES, LTD. (JP) 2002-06-13 US disclosed
EP-1207162-A1 7a-alkoxy-4H-pyrano-[3,2-d]-oxazol-2(3H)-one and process for producing the same Ube Industries, Ltd. (JP) 2002-05-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020072612-A1 7a-alkoxy-4H-pyrano [3,2-d] -oxazol-2 (3H) -one and process for producing the same ACSL1, ACSL4, ACSL3 TP53 4362/4885HPGD 1274/4885TLR7 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.