Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | ALPL | P05186 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.60 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725699 | 0.81 | ALDH1A1 (0.51) | DCUN1D1NPC1RAB9ACYP1A2ALPL | |
| SCHEMBL10944351 | 0.79 | NR1H2 (0.77) | DCUN1D1NPC1RAB9ACYP1A2ALPL | |
| SCHEMBL1399839 | 0.76 | ALDH1A1 (0.57) | CYP1A2ALPLCYP3A4HPGDCYP2C19 | |
| SCHEMBL31305459 | 0.76 | ALDH1A1 (0.57) | CYP1A2ALPLCYP3A4HPGDCYP2C19 | |
| SCHEMBL2847578 | 0.72 | KDM4E (1.00) | DCUN1D1NPC1RAB9ACYP1A2ALPL | |
| Water SCHEMBL11347314 | 0.71 | ALDH1A1 (0.51) | NPC1RAB9ACYP1A2ALPLSMN1; SMN2 | |
| SCHEMBL15657194 | 0.70 | NR1H2 (0.55) | DCUN1D1NPC1RAB9ACYP1A2ALPL | |
| SCHEMBL28580098 | 0.70 | HSD17B10 (0.58) | DCUN1D1NPC1RAB9ACYP1A2ALPL | |
| SCHEMBL5959950 | 0.70 | SMN1; SMN2 (0.69) | DCUN1D1NPC1RAB9ACYP1A2ALPL | |
| SCHEMBL18284726 | 0.70 | ALDH1A1 (0.66) | DCUN1D1CYP1A2ALPLALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750545-A | EXHIBIT EOSINOPHIL-INHIBITORY ACTION AND LYMPHOCYTE ACTIVATION-INHIBITORY ACTION; USEFUL FOR TREATMENT OF IMMUNE-RELATED DISEASES | THE GREEN CROSS CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0710654-A1 | TRIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-08 | — | — | EP | disclosed |