Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALPL | P05186 | 2/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725571 | 0.81 | DCUN1D1 (0.62) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL31305459 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL1399839 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL10822462 | 0.72 | HTR2B (0.55) | ALDH1A1KDM4ECYP1A2KMT2ACYP2A6 | |
| SCHEMBL8731214 | 0.69 | ALPL (0.66) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL2847578 | 0.69 | KDM4E (1.00) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL21223540 | 0.67 | CYP1A2 (0.48) | KDM4ECYP1A2KMT2AMEN1CYP2A6 | |
| SCHEMBL2493952 | 0.66 | KDM4E (0.58) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL29494605 | 0.66 | CYP2A6 (1.00) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 | |
| SCHEMBL2473555 | 0.66 | CYP2A6 (1.00) | ALDH1A1KDM4ECYP1A2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750545-A | EXHIBIT EOSINOPHIL-INHIBITORY ACTION AND LYMPHOCYTE ACTIVATION-INHIBITORY ACTION; USEFUL FOR TREATMENT OF IMMUNE-RELATED DISEASES | THE GREEN CROSS CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0710654-A1 | TRIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-08 | — | — | EP | disclosed |