Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 12/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15215399 | 0.99 | APAF1 (0.44) | APAF1RAB9AUSP2L3MBTL1APP | |
| Hydrochloric Acid SCHEMBL29356681 | 0.89 | MEN1 (0.47) | APAF1RAB9AUSP2L3MBTL1APP | |
| SCHEMBL23675025 | 0.89 | APP (0.40) | APAF1RAB9AUSP2L3MBTL1APP | |
| SCHEMBL29461572 | 0.88 | MEN1 (0.48) | RAB9AUSP2L3MBTL1APPMEN1 | |
| SCHEMBL6128296 | 0.88 | MEN1 (0.48) | RAB9AUSP2L3MBTL1APPMEN1 | |
| SCHEMBL10071791 | 0.86 | APAF1 (0.58) | APAF1RAB9AUSP2L3MBTL1APP | |
| SCHEMBL15397117 | 0.84 | MEN1 (0.43) | RAB9AUSP2L3MBTL1APPMEN1 | |
| SCHEMBL20329155 | 0.84 | MEN1 (0.39) | APAF1RAB9AUSP2L3MBTL1APP | |
| SCHEMBL11955374 | 0.82 | KDM4E (0.47) | RAB9AUSP2APPMEN1KMT2A | |
| SCHEMBL13810526 | 0.81 | APP (0.43) | RAB9AUSP2L3MBTL1APPMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741662-A | Direct stain specific binding assays for microorganisms | QUIDEL CORPORATION (US) | 1998-04-21 | — | — | US | disclosed |