Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL910176 | 0.73 | ITGB2 (0.37) | MAPTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL6216565 | 0.67 | ITGB2 (0.39) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL3345615 | 0.64 | ITGB2 (0.36) | MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL62556 | 0.64 | ITGB2 (0.36) | SMN1; SMN2ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL8725276 | 0.61 | BRAF (0.45) | MAOBMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15786696 | 0.61 | ABCB1 (0.60) | ABCB1FLT1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL395770 | 0.60 | ALDH1A1 (0.50) | MAPTSMN1; SMN2KMT2AMEN1RAB9A | |
| SCHEMBL8616603 | 0.60 | ITGB2 (0.32) | — | |
| SCHEMBL6346532 | 0.60 | CTNNB1 (0.35) | ALDH1A1KDM4ELMNATDP1L3MBTL1 | |
| SCHEMBL62903 | 0.60 | MTNR1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832091-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040705-A1 | C-4' MODIFIED ADENOSINE KINASE INHIBITORS | GENSIA SICOR (US) | 1996-12-19 | — | — | WO | disclosed |