Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783597 | 0.80 | KMT2A (0.63) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL19668743 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL4361229 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL31724491 | 0.78 | KMT2A (0.74) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL15745601 | 0.76 | CYP1A2 (0.55) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11689283 | 0.76 | CTSD (0.42) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL21378747 | 0.76 | CYP1A2 (0.55) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL21378793 | 0.76 | CYP1A2 (0.55) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL9574957 | 0.75 | CTSD (0.63) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL13516453 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876370-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997025325-A1 | CARBAPENEM COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-07-17 | — | — | WO | disclosed |