Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4361229 | 0.84 | SMN1; SMN2 (0.66) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL19668743 | 0.84 | SMN1; SMN2 (0.66) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL31724491 | 0.80 | KMT2A (0.74) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8725874 | 0.80 | SMN1; SMN2 (0.57) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL13516453 | 0.78 | SMN1; SMN2 (1.00) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL21933011 | 0.77 | CYP1A2 (0.45) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL27361704 | 0.77 | ALDH1A1 (0.60) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL8836716 | 0.77 | ALDH1A1 (0.60) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL7719801 | 0.75 | ALDH1A1 (0.59) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL3767996 | 0.75 | SLC6A3 (0.52) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651604-B1 | N-´2-(2-PYRIDINYL)ETHYL BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-11-12 | — | — | EP | claimed |
| US-7723364-B2 | N-[2-(2-pyridinyl) ethyl]benzamide compounds and their use as fungicides | BAYER CROPSCIENCE SA (FR) | 2010-05-25 | — | — | US | claimed |
| US-20060246102-A1 | N-'2-(2-pyridinyl) ethylbenzamide compounds and their use as fungicides | BAYER SAS (FR) | 2006-11-02 | — | — | US | claimed |
| EP-1651604-A2 | N-¬2-(2-PYRIDINYL)ETHYL|BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | Bayer CropScience S.A. (FR) | 2006-05-03 | — | — | EP | claimed |
| WO-2005014545-A2 | N-′2-(2-PYRIDINYL) ETHYLBENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE S.A. (FR) | 2005-02-17 | — | — | WO | claimed |
| EP-1500651-A1 | N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-01-26 | — | — | EP | claimed |
| EP-1694648-B1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER SAS (FR) | 2015-07-29 | — | — | EP | disclosed |
| EP-1720865-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2014-12-31 | — | — | EP | disclosed |
| EP-1651604-B1 | N-´2-(2-PYRIDINYL)ETHYL BENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-11-12 | — | — | EP | disclosed |
| EP-1694649-B1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2014-01-22 | — | — | EP | disclosed |
| US-8318777-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2012-11-27 | — | — | US | disclosed |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER SAS (FR) | 2012-03-22 | — | — | US | disclosed |
| US-8071627-B2 | 2-pyridinylethylcarboxamide derivatives and their use as fungicides | BAYER SAS (FR) | 2011-12-06 | — | — | US | disclosed |
| WO-2005085238-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-09-15 | — | — | WO | disclosed |
| EP-1574511-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2005058828-A1 | 2-PYRIDINYLETHYLBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE S.A. (FR) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005058833-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2005-06-30 | — | — | WO | disclosed |
| EP-1548007-A1 | 2-Pyridinylethylcarboxamide derivatives and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-06-29 | — | — | EP | disclosed |
| WO-2005014545-A2 | N-′2-(2-PYRIDINYL) ETHYLBENZAMIDE COMPOUNDS AND THEIR USE AS FUNGICIDES | BAYER CROPSCIENCE S.A. (FR) | 2005-02-17 | — | — | WO | disclosed |
| EP-1500651-A1 | N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides | Bayer CropScience S.A. (FR) | 2005-01-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060246102-A1 | N-'2-(2-pyridinyl) ethylbenzamide compounds and their use as fungicides | CYP1A2, CYP4B1, CYP1B1 | KMT2A 1783/4885SMN1; SMN2 1751/4885MEN1 1223/4885 |
| US-20120071517-A1 | 2-PYRIDINYLETHYLCARBOXAMIDE DERIVATIVES AND THEIR USE AS FUNGICIDES | CYP1A2, CYP51A1, CYP3A5 | KMT2A 817/4885SMN1; SMN2 3882/4885MEN1 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.