Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8725944 | 0.76 | HRH3 (0.34) | DRD2SLC6A4HRH3 | |
| SCHEMBL8721036 | 0.75 | DRD2 (0.39) | DRD2SLC6A4HRH3OPRM1OPRK1 | |
| SCHEMBL8721050 | 0.72 | MEN1 (0.35) | DRD2SLC6A4HRH3OPRM1OPRK1 | |
| SCHEMBL8723636 | 0.72 | RAB9A (0.39) | DRD2SLC6A4HRH3OPRM1OPRK1 | |
| SCHEMBL8723720 | 0.71 | DRD2 (0.35) | DRD2SLC6A4HRH3OPRM1OPRK1 | |
| SCHEMBL30909231 | 0.71 | DRD2 (0.54) | DRD2SLC6A4OPRM1OPRK1 | |
| SCHEMBL8706248 | 0.70 | HRH3 (0.41) | DRD2SLC6A4HRH3 | |
| SCHEMBL8722116 | 0.70 | HRH3 (0.43) | DRD2SLC6A4HRH3OPRM1OPRK1 | |
| SCHEMBL8721868 | 0.69 | HRH3 (0.34) | DRD2SLC6A4HRH3 | |
| SCHEMBL8722113 | 0.69 | CHRM2 (0.48) | DRD2SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073845-A1 | METHODS AND PHARMACOLOGICAL AGENTS FOR INCREASING EXPANSION, ENGRAFTMENT OR IMMUNE OUTPUT OF HUMAN HEMATOPOIETIC STEM CELLS IN TRANSPLANTATION AND DISEASE SETTINGS | VALORISATION HSJ, LIMITED PARTNERSHIP (CA) | 2024-04-11 | — | — | WO | disclosed |
| EP-0875513-A1 | Substituted heteroaromatic 5-HT 1F agonists | ELI LILLY AND COMPANY (US) | 1998-11-04 | — | — | EP | disclosed |