Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | FPR3 | P25089 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721666 | 0.91 | F2 (0.35) | F2F10PRSS1FPR3FPR2 | |
| SCHEMBL6477345 | 0.85 | F2 (0.35) | F2EPHX2F10PRSS1MEN1 | |
| SCHEMBL7049353 | 0.85 | F2 (0.35) | F2EPHX2F10PRSS1MEN1 | |
| SCHEMBL6487727 | 0.85 | F2 (0.36) | F2EPHX2F10PRSS1MEN1 | |
| SCHEMBL6483104 | 0.81 | PDE4A (0.38) | F2EPHX2F10PRSS1MEN1 | |
| SCHEMBL7047781 | 0.81 | PDE4A (0.38) | F2EPHX2F10PRSS1MEN1 | |
| SCHEMBL8933084 | 0.81 | F2 (0.33) | F2F10 | |
| SCHEMBL7049587 | 0.80 | F2 (0.33) | F2EPHX2MEN1KMT2A | |
| SCHEMBL8933063 | 0.80 | P2RX7 (0.34) | F2EPHX2MEN1KMT2A | |
| SCHEMBL8727226 | 0.80 | F2 (0.34) | F2F10PRSS1QRFPRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |
| WO-1996025426-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |