Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 6/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902186 | 0.90 | FOLH1 (0.58) | KMT2ALMNAFOLH1FPR2HDAC1 | |
| SCHEMBL4458797 | 0.90 | FOLH1 (0.58) | KMT2ALMNAFOLH1FPR2HDAC1 | |
| Hydrochloric Acid SCHEMBL7903946 | 0.89 | FOLH1 (0.57) | KMT2ALMNAFOLH1FPR2HDAC1 | |
| SCHEMBL8723910 | 0.84 | KMT2A (0.42) | KMT2ALMNACA1CA2FOLH1 | |
| SCHEMBL8727524 | 0.82 | KMT2A (0.67) | KMT2ALMNACA1CA2HDAC2 | |
| SCHEMBL8721907 | 0.81 | LMNA (0.47) | KMT2ALMNACA1CA2JAK2 | |
| SCHEMBL20334999 | 0.81 | KMT2A (0.74) | KMT2ACA1CA2FOLH1JAK2 | |
| SCHEMBL20334998 | 0.81 | KMT2A (0.74) | KMT2ACA1CA2FOLH1JAK2 | |
| Trifluoroacetic Acid SCHEMBL29966022 | 0.81 | LMNA (0.46) | KMT2ALMNACA1CA2HDAC1 | |
| SCHEMBL20335123 | 0.80 | KMT2A (0.58) | KMT2ALMNACA1CA2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651740-B1 | AMINO ACID LINKED NITROGEN MUSTARD DERIVATIVES AND THEIR USE AS PRODRUGS IN THE TREATMENT OF TUMOURS | ZENECA LTD (GB) | 1998-10-21 | — | — | EP | claimed |