Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.39 |
| ▸ | FPR2 | P25090 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4460828 | 0.92 | FOLH1 (0.48) | FOLH1 | |
| SCHEMBL7902175 | 0.92 | FOLH1 (0.48) | FOLH1 | |
| SCHEMBL8815091 | 0.85 | NAALAD2 (0.46) | FOLH1FPR2 | |
| SCHEMBL8726206 | 0.84 | KMT2A (0.51) | KMT2ACA2CA1JAK2FOLH1 | |
| SCHEMBL8721870 | 0.83 | CA2 (0.53) | KMT2ACA2CA1 | |
| SCHEMBL8722915 | 0.81 | FOLH1 (0.48) | FOLH1FPR2 | |
| SCHEMBL7894806 | 0.80 | FOLH1 (0.49) | FOLH1FPR2LMNAATM | |
| SCHEMBL7906574 | 0.80 | FOLH1 (0.49) | FOLH1FPR2LMNAATM | |
| SCHEMBL7900456 | 0.79 | FOLH1 (0.48) | FOLH1FPR2LMNAATM | |
| SCHEMBL8815104 | 0.78 | CCKBR (0.51) | KMT2ACA2CA1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651740-B1 | AMINO ACID LINKED NITROGEN MUSTARD DERIVATIVES AND THEIR USE AS PRODRUGS IN THE TREATMENT OF TUMOURS | ZENECA LTD (GB) | 1998-10-21 | — | — | EP | claimed |