Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726210 | 1.00 | HCRTR2 (0.39) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL8726254 | 0.96 | HCRTR2 (0.38) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL8726255 | 0.96 | HCRTR2 (0.38) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL5836563 | 0.92 | DRD2 (0.40) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL5836573 | 0.92 | DRD2 (0.40) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL5836076 | 0.88 | HCRTR2 (0.40) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL5836080 | 0.88 | HCRTR2 (0.40) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL9239246 | 0.78 | DRD2 (0.36) | HCRTR2DRD2HTR1DHTR1BCYP1A2 | |
| SCHEMBL7913981 | 0.77 | DRD2 (0.35) | HCRTR2DRD2HTR1DHTR1BMEN1 | |
| SCHEMBL5836960 | 0.77 | ALOX5AP (0.35) | HCRTR2DRD2HCRTR1HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753142-A | Nematic liquid-crystal composition for active matrix application | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |