Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726254 | 1.00 | HCRTR2 (0.38) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL8726210 | 0.96 | HCRTR2 (0.39) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL8726207 | 0.96 | HCRTR2 (0.39) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL5836573 | 0.91 | DRD2 (0.40) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL5836563 | 0.91 | DRD2 (0.40) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL5836080 | 0.87 | HCRTR2 (0.40) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL5836076 | 0.87 | HCRTR2 (0.40) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL7913981 | 0.81 | DRD2 (0.35) | HCRTR2DRD2HTR1DHTR1BDRD1 | |
| SCHEMBL8729394 | 0.80 | HCRTR2 (0.36) | HCRTR2DRD2DRD1DRD4DRD5 | |
| SCHEMBL15256110 | 0.79 | GAA (0.39) | DRD2DRD3GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753142-A | Nematic liquid-crystal composition for active matrix application | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |
| EP-0406468-B1 | NEMATIC-LIQUID-CRYSTAL COMPOSITION FOR ACTIVE MATRIX APPLICATION | SHARP CORPORATION (JP) | 1992-10-21 | — | — | EP | disclosed |