Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6851140 | 1.00 | KDM4E (0.57) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL8727246 | 0.88 | KDM4E (0.72) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL6851166 | 0.88 | KDM4E (0.72) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL162075 | 0.84 | KDM4E (0.77) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL162076 | 0.84 | KDM4E (0.77) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL8489579 | 0.80 | KDM4E (0.70) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL8489573 | 0.80 | KDM4E (0.70) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL5859861 | 0.80 | KDM4E (0.50) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL5859863 | 0.80 | KDM4E (0.50) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL7822146 | 0.77 | KDM4E (0.47) | KDM4EARMAPTCYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |