Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286021 | 0.82 | MAPT (0.60) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL8488782 | 0.81 | LMNA (0.51) | ALDH1A1LMNAMAPTHSD17B10CYP1A2 | |
| SCHEMBL5859861 | 0.78 | KDM4E (0.50) | KDM4EARNPC1RAB9AMAPT | |
| SCHEMBL5859863 | 0.78 | KDM4E (0.50) | KDM4EARNPC1RAB9AMAPT | |
| SCHEMBL6852630 | 0.78 | ABCG2 (0.57) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL6852627 | 0.78 | ABCG2 (0.57) | KDM4EALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL9786077 | 0.78 | KDM4E (0.47) | KDM4EARHSD17B10CYP1A2MAOB | |
| SCHEMBL9786078 | 0.78 | KDM4E (0.47) | KDM4EARHSD17B10CYP1A2MAOB | |
| SCHEMBL6851140 | 0.77 | KDM4E (0.57) | KDM4EARMAPTHSD17B10CYP1A2 | |
| SCHEMBL8726252 | 0.77 | KDM4E (0.57) | KDM4EARMAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |