Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722059 | 0.86 | ADAMTS5 (0.40) | RAB9ANPC1ADRB2ADRB1ADRB3 | |
| SCHEMBL8722966 | 0.81 | ADAMTS5 (0.37) | RAB9ANPC1ADAMTS4ADAMTS5 | |
| SCHEMBL8726187 | 0.81 | ADAMTS5 (0.36) | RAB9ANPC1MAPTADAMTS4ADAMTS5 | |
| SCHEMBL8726175 | 0.81 | ADAMTS5 (0.36) | RAB9ANPC1ADAMTS4ADAMTS5 | |
| SCHEMBL6778559 | 0.80 | MAPT (0.53) | PPARGPPARARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8726195 | 0.79 | NPC1 (0.38) | PPARGPPARARAB9ANPC1ALDH1A1 | |
| SCHEMBL2247466 | 0.78 | ADAMTS5 (0.44) | RAB9ANPC1ADAMTS4ADAMTS5 | |
| SCHEMBL12356373 | 0.78 | ADAMTS5 (0.44) | RAB9ANPC1ADAMTS4ADAMTS5 | |
| SCHEMBL7902794 | 0.77 | KMT2A (0.47) | PPARGPPARATP53MAPTALDH1A1 | |
| SCHEMBL29170202 | 0.77 | PPARG (0.48) | PPARGPPARARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |