Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CBX4 | O00257 | 2/20 | 0.33 |
| ▸ | CBX7 | O95931 | 2/20 | 0.33 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.33 |
| ▸ | CBX8 | Q9HC52 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8721920 | 0.93 | DHFR (0.34) | P2RY12DHFRCBX4CBX7CDYL2 | |
| SCHEMBL8726187 | 0.92 | ADAMTS5 (0.36) | ADAMTS5ADAMTS4P2RY12NOD2DHFR | |
| SCHEMBL8726175 | 0.92 | ADAMTS5 (0.36) | ADAMTS5ADAMTS4P2RY12NOD2DHFR | |
| SCHEMBL8726173 | 0.91 | NOD2 (0.33) | ADAMTS5ADAMTS4P2RY12NOD2DHFR | |
| SCHEMBL8723006 | 0.85 | DHFR (0.33) | ADAMTS5P2RY12DHFRMMP2MMP8 | |
| SCHEMBL8722059 | 0.85 | ADAMTS5 (0.40) | ADAMTS5ADAMTS4P2RY12NOD2NPC1 | |
| SCHEMBL8724211 | 0.84 | MAPT (0.41) | RAB9AHRH3 | |
| SCHEMBL8726470 | 0.81 | PPARG (0.42) | ADAMTS5ADAMTS4NPC1RAB9A | |
| SCHEMBL9751830 | 0.81 | EGFR (0.45) | P2RY12DHFR | |
| SCHEMBL8726491 | 0.80 | CA2 (0.47) | ADAMTS5ADAMTS4DHFRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |