Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28884491 | 0.86 | TRPA1 (0.50) | TRPA1LMNAKDM4ETAAR1 | |
| SCHEMBL9479604 | 0.85 | TRPA1 (0.68) | TRPA1LMNAALDH1A1KDM4ETAAR1 | |
| SCHEMBL11328686 | 0.85 | TRPA1 (0.52) | TRPA1LMNAALDH1A1KDM4EAOC3 | |
| Hydrochloric Acid SCHEMBL27894902 | 0.84 | TAAR1 (0.45) | TRPA1LMNAALDH1A1TAAR1AOC3 | |
| SCHEMBL27620644 | 0.83 | TRPA1 (0.56) | TRPA1LMNAALDH1A1KDM4ETAAR1 | |
| SCHEMBL9820021 | 0.82 | TRPA1 (0.53) | TRPA1LMNAALDH1A1KDM4ETAAR1 | |
| SCHEMBL148756 | 0.81 | TRPA1 (0.48) | TRPA1LMNAKDM4ETAAR1 | |
| SCHEMBL5181221 | 0.81 | TRPA1 (0.47) | TRPA1LMNAALDH1A1KDM4ETAAR1 | |
| SCHEMBL1774828 | 0.80 | LMNA (0.46) | TRPA1LMNAALDH1A1TAAR1 | |
| SCHEMBL19294780 | 0.78 | TAAR1 (0.56) | TRPA1TAAR1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102329194-A | Preparation method of ibuprofen intermediate p-isobutylphenethyl alcohol | UNIV ZHEJIANG TECHNOLOGY | 2012-01-25 | — | — | CN | claimed |
| JP-3191796-A | — | — | None | — | — | JP | disclosed |
| JP-1311043-A | — | — | None | — | — | JP | disclosed |
| CN-112955250-B | Method and device for carrying out chemical reactions under elevated pressure | 巴斯夫欧洲公司 | 2024-06-11 | — | — | CN | disclosed |
| US-11850578-B2 | Method and apparatus for performing a chemical reaction under elevated pressure | BASF SE (DE) | 2023-12-26 | — | — | US | disclosed |
| US-20210322941-A1 | METHOD AND APPARATUS FOR PERFORMING A CHEMICAL REACTION UNDER ELEVATED PRESSURE | BASF SE (DE) | 2021-10-21 | — | — | US | disclosed |
| CN-113244117-A | Composition providing delayed release of active substances | 诺赛尔股份有限公司 | 2021-08-13 | — | — | CN | disclosed |
| EP-3852914-A1 | METHOD AND APPARATUS FOR PERFORMING A CHEMICAL REACTION UNDER ELEVATED PRESSURE | BASF SE (DE) | 2021-07-28 | — | — | EP | disclosed |
| CN-107107019-B | Coated microcapsules | 诺赛尔股份有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-112955250-A | Method and apparatus for conducting chemical reactions at elevated pressures | 巴斯夫欧洲公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-1016432-B | Salicylic acid copolymer and method for preparing metal salt thereof | MITSUI TOATSU CHEMICAIS INC (JP) | 1992-04-29 | — | — | CN | disclosed |
| JP-H03191796-A | PRODUCTION OF OPTICALLY ACTIVE 1-PARA-ISOBUTYLPHENYLETHANOL AND ITS CARBOXYLIC ACID ESTER | DAICEL CHEM IND LTD | 1991-08-21 | — | — | JP | disclosed |
| CN-1051368-A | Salicylic acid copolymers and its metal-salt and preparation method thereof contain the developer of this metal salts of copolymers and the colour developing paper of this developer of employing | MITSUI TOATSU CHEMICALS (JP) | 1991-05-15 | — | — | CN | disclosed |
| JP-H01311043-A | PROCESS FOR RECYCING CATALYST IN CARBONYLATION OF ISOBUTYLPHENYL ETHANOL INTO IBUPROFEN | HOECHST CELANESE CORP | 1989-12-15 | — | — | JP | disclosed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| EP-0337803-A1 | Catalyst recycle in the carbonylation of isobutylphenylethanol to ibuprofen | HOECHST CELANESE CORPORATION (US) | 1989-10-18 | — | — | EP | disclosed |
| CN-87107802-A | Salicylic acid copolymer and metal salt thereof, process for producing the same, color-developing agent containing the copolymer metal salt, and color-developing paper using the color-developing agent | — | 1988-08-10 | — | — | CN | disclosed |
| US-4601797-A | Electrochemical carboxylation of p-isobutylacetophenone and other aryl ketones | MONSANTO COMPANY (US) | 1986-07-22 | — | — | US | disclosed |
| US-4582577-A | Electrochemical carboxylation of p-isobutylacetophenone | MONSANTO COMPANY (US) | 1986-04-15 | — | — | US | disclosed |