SCHEMBL872707

SCHEMBL872707

CCCCc1cc(CC)cc(CCCC)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.47
HTT P42858 2/20 0.45
NPC1 O15118 1/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
ALOX5 P09917 5/20 0.44
HSPA5 P11021 1/20 0.44
PTGS2 P35354 7/20 0.43
EGFR P00533 2/20 0.43
CYP3A4 P08684 3/20 0.42
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41
TP53 P04637 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1312038 0.96 TYR (0.44) TYRHTTNPC1HPGDMAPK1
SCHEMBL1020399 0.96 EGFR (0.44) TYRHTTNPC1HPGDMAPK1
SCHEMBL600371 0.94 HSPA5 (0.53) TYRHTTNPC1HPGDMAPK1
SCHEMBL29427951 0.94 HSPA5 (0.53) TYRHTTNPC1HPGDMAPK1
SCHEMBL11673558 0.92 PTGS2 (0.53) TYRHTTALOX5PTGS2EGFR
SCHEMBL28575548 0.92 PTGS2 (0.53) TYRHTTALOX5PTGS2EGFR
SCHEMBL9614548 0.92 PTGS2 (0.53) TYRHTTALOX5PTGS2EGFR
SCHEMBL1021654 0.90 ALOX5 (0.49) TYRHTTALOX5PTGS2EGFR
SCHEMBL5678269 0.90 HTT (0.50) TYRHTTNPC1HPGDMAPK1
SCHEMBL201692 0.89 NPC1 (0.57) TYRHTTNPC1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109476077-B Method and composition for forming three-dimensional objects by additive fabrication 科思创(荷兰)有限公司 2022-04-26 CN disclosed
CN-109562567-B Method and composition for forming three-dimensional objects by additive fabrication 科思创(荷兰)有限公司 2022-04-05 CN disclosed
CN-108641789-B Refrigerating machine oil composition matched with R32 and preparation method thereof 中国石油化工股份有限公司 2020-11-06 CN disclosed
CN-111454764-A Hydrocarbon gas compressor oil composition and preparation method thereof 中国石油化工股份有限公司 2020-07-28 CN disclosed
CN-108641789-A A kind of and mating R32 refrigerated machine oil composition and preparation method thereof 中国石油化工股份有限公司 2018-10-12 CN disclosed
CN-107406786-A Aromatic tetrahedral borate compounds for lubricating compositions 路博润公司 2017-11-28 CN disclosed
US-8143324-B2 antioxidants with hindered phenol functionality perform better in curing of polybenzocyclobutene materials in air without undue degradation of key properties DOW GLOBAL TECHNOLOGIES LLC (US) 2012-03-27 US disclosed
EP-2042547-B1 Benzocyclobutene based polymer formulations DOW GLOBAL TECHNOLOGIES INC (US) 2010-12-22 EP disclosed
US-7807757-B2 stabilizing and at the same time phase compatibilizing plastics or plastic compositions by incorporating maleic anhydride or acrylic acid grafted copolymer or terpolymer (styrene/butadiene/styrene block copolymer grafted with maleic anhydride) obtained by reacting with a benzotriazole compound CIBA SPECIALTY CHEMICALS CORP. (US) 2010-10-05 US disclosed
US-20100227143-A1 PROCESS FOR FORMING IMPROVED FIBER REINFORCED COMPOSITES AND COMPOSITES THEREFROM TICONA, LLC 2010-09-09 US disclosed
US-20080051521-A1 Functionalized polymers PFAENDNER RUDOLF 2008-02-28 US disclosed
EP-1279754-B1 Metallocene catalyzed propylene-alpha-olefin random copolymer melt spun fiber TOTAL PETROCHEMICALS RES FELUY (BE) 2006-08-30 EP disclosed
US-6608225-B1 Esterification of alkali metal acrylate with a 3-chloroiso-butylalkoxysilane; adhesion promoters, protective coatings DEGUSSA AG (DE) 2003-08-19 US disclosed
EP-1279754-A2 Metallocene catalyzed propylene-alpha-olefin random copolymer melt spun fiber FINA TECHNOLOGY, INC. (US) 2003-01-29 EP disclosed
US-6476172-B1 Metallocene catalyzed propylene-α-olefin random copolymer melt spun fibers FINA TECHNOLOGY, INC. 2002-11-05 US disclosed
EP-0319924-B1 Process for producing thermoplastic resin composition IDEMITSU PETROCHEMICAL CO (JP) 1995-11-22 EP disclosed
EP-0206034-B1 POLYOLEFIN COMPOSITION IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1992-01-22 EP disclosed
US-5013773-A Granulated magnesium oxysulfate fiber reinforcement IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-05-07 US disclosed
US-4990554-A Propylene an dethylene homo- and copolymers with filler; appliances, offices devices and automobiles IDEMITSU PETROCHEMICAL COMPANY LIMITED (JP) 1991-02-05 US disclosed
EP-0206034-A1 Polyolefin composition IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1986-12-30 EP disclosed