Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726826 | 0.84 | PPARA (0.47) | PPARAL3MBTL1PTPN1 | |
| SCHEMBL8726833 | 0.84 | PPARA (0.47) | PPARAL3MBTL1PTPN1 | |
| SCHEMBL8726816 | 0.84 | PPARA (0.47) | PPARAL3MBTL1PTPN1 | |
| SCHEMBL8758086 | 0.81 | TSHR (0.47) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL3004957 | 0.81 | FFAR1 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL13886735 | 0.80 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8732784 | 0.79 | POLB (0.47) | L3MBTL1 | |
| SCHEMBL13886736 | 0.79 | FFAR1 (0.56) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL4446760 | 0.78 | MEN1 (0.55) | NPC1RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8728998 | 0.78 | CA2 (0.48) | NPC1RAB9AKMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |