Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | YAP1 | P46937 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726826 | 1.00 | PPARA (0.47) | PPARAITGB3ITGA2BPPARGBCL2 | |
| SCHEMBL8726816 | 1.00 | PPARA (0.47) | PPARAITGB3ITGA2BPPARGBCL2 | |
| SCHEMBL8727138 | 0.84 | NPC1 (0.44) | PPARAPTPN1L3MBTL1 | |
| SCHEMBL8727035 | 0.83 | ACACB (0.46) | ITGB3ITGA2BHDAC8ACACB | |
| SCHEMBL19930027 | 0.81 | BCL2 (0.59) | PPARAITGB3ITGA2BPPARGBCL2 | |
| SCHEMBL12532786 | 0.81 | BCL2 (0.59) | PPARAITGB3ITGA2BPPARGBCL2 | |
| SCHEMBL8729688 | 0.81 | MAOB (0.42) | L3MBTL1ENPP2 | |
| SCHEMBL8729697 | 0.81 | MAOB (0.42) | L3MBTL1ENPP2 | |
| SCHEMBL8729694 | 0.81 | MAOB (0.42) | L3MBTL1ENPP2 | |
| SCHEMBL8729106 | 0.80 | ADRB3 (0.49) | ITGB3ITGA2BBCL2HDAC8PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |