Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | CNR1 | P21554 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | F7 | P08709 | 4/20 | 0.57 |
| ▸ | F3 | P13726 | 4/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.57 |
| ▸ | PPARD | Q03181 | 3/20 | 0.57 |
| ▸ | PPARA | Q07869 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27843812 | 0.98 | MGLL (0.69) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL11782881 | 0.94 | DGKA (0.62) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL28690034 | 0.94 | DGKA (0.62) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL11782893 | 0.94 | DGKA (0.62) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL30763826 | 0.90 | MGLL (0.66) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL31758884 | 0.90 | MGLL (0.66) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL7639501 | 0.89 | MGLL (0.77) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL4813543 | 0.89 | MGLL (0.77) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL4813525 | 0.89 | MGLL (0.77) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL10086074 | 0.89 | MGLL (0.77) | MGLLALDH1A1MAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823897-A1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034858-A1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |