Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635701 | 0.89 | MMP3 (0.74) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30071626 | 0.84 | MMP3 (0.62) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL3100592 | 0.84 | MMP3 (0.62) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| Guanidine SCHEMBL27689978 | 0.83 | MMP3 (0.61) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL7110749 | 0.83 | MMP3 (0.61) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6633131 | 0.81 | ALDH1A1 (0.82) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6633920 | 0.81 | MMP3 (0.62) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15126359 | 0.79 | PLK1 (0.73) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL1794660 | 0.79 | MMP3 (0.65) | MMP3HDAC8ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5456246 | 0.79 | CA1 (0.71) | ALDH1A1SMN1; SMN2HPGDRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750545-A | EXHIBIT EOSINOPHIL-INHIBITORY ACTION AND LYMPHOCYTE ACTIVATION-INHIBITORY ACTION; USEFUL FOR TREATMENT OF IMMUNE-RELATED DISEASES | THE GREEN CROSS CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0710654-A1 | TRIAZOLE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | THE GREEN CROSS CORPORATION (JP) | 1996-05-08 | — | — | EP | disclosed |