Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6485834 | 0.78 | F2 (0.48) | F2 | |
| SCHEMBL6487722 | 0.78 | F2 (0.50) | F2 | |
| SCHEMBL8809659 | 0.75 | KDM4E (0.59) | F2 | |
| SCHEMBL21088553 | 0.72 | KMT2A (0.50) | MEN1KMT2APOLB | |
| SCHEMBL21088503 | 0.72 | HTT (0.50) | MEN1KMT2A | |
| SCHEMBL10143558 | 0.71 | PRSS1 (0.55) | PRSS1F2F10MEN1KMT2A | |
| SCHEMBL5568118 | 0.71 | EPHX2 (0.51) | PRSS1F2PDE4APDE4BPDE4C | |
| SCHEMBL5568337 | 0.70 | EPHX2 (0.50) | PRSS1F2PDE4APDE4BPDE4C | |
| SCHEMBL11684656 | 0.70 | PRSS1 (0.54) | PRSS1F2F10MEN1KMT2A | |
| SCHEMBL24872851 | 0.70 | MEN1 (0.48) | MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873356-A1 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1998-10-28 | — | — | EP | disclosed |