Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 9/20 | 0.54 |
| ▸ | HTR2B | P41595 | 6/20 | 0.54 |
| ▸ | HTR2A | P28223 | 4/20 | 0.54 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483706 | 0.82 | HTR2C (0.59) | KDM4EHTR2CHTR2BHTR2AGID4 | |
| SCHEMBL6483702 | 0.82 | HTR2C (0.59) | KDM4EHTR2CHTR2BHTR2AGID4 | |
| Hydrochloric Acid SCHEMBL8377589 | 0.81 | HTR2C (0.58) | KDM4EHTR2CHTR2BHTR2AGID4 | |
| Hydrochloric Acid SCHEMBL7044040 | 0.81 | HTR2C (0.58) | KDM4EHTR2CHTR2BHTR2AGID4 | |
| SCHEMBL8809131 | 0.79 | HTR2C (0.64) | KDM4EHTR2CHTR2BHDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL5900833 | 0.78 | HTR2C (0.62) | KDM4EHTR2CHTR2BHDAC1HDAC3 | |
| Hydrochloric Acid SCHEMBL5900838 | 0.78 | HTR2C (0.62) | KDM4EHTR2CHTR2BHDAC1HDAC3 | |
| Trifluoroacetic Acid SCHEMBL18670028 | 0.76 | KDM4E (0.55) | KDM4EHTR2CHTR2BHTR2AGID4 | |
| Trifluoroacetic Acid SCHEMBL18670029 | 0.76 | KDM4E (0.55) | KDM4EHTR2CHTR2BHTR2AGID4 | |
| SCHEMBL8727237 | 0.75 | PRSS1 (0.45) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996025426-A9 | NOVEL DIPEPTIDE AMIDINES AS THROMBIN INHIBITORS | — | 1997-06-12 | — | — | WO | disclosed |