Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 12/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727254 | 0.85 | TLR7 (0.43) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL8722625 | 0.85 | TLR7 (0.62) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL8722638 | 0.83 | TLR7 (0.39) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL1895460 | 0.77 | TLR7 (0.73) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL8721690 | 0.76 | CYP1A2 (0.40) | TLR7CYP1A2NTRK1 | |
| SCHEMBL9601821 | 0.75 | IKBKB (0.46) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL9602030 | 0.75 | TLR7 (0.47) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL10732746 | 0.74 | TLR7 (0.51) | TLR7NUDT1LMNAPOLBHRH2 | |
| SCHEMBL8721716 | 0.73 | TLR7 (0.40) | TLR7TLR8 | |
| SCHEMBL6105965 | 0.72 | TLR7 (0.56) | TLR7NUDT1LMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756747-A | 1H-imidazo 4,5-c!quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0385630-B1 | 1H-imidazo(4,5-c)Quinolin-4-amines as antivirals | RIKER LABORATORIES INC (US) | 1996-11-27 | — | — | EP | disclosed |
| EP-0389302-B1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES INC (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5037986-A | Olefinic 1H-imidazo[4,5-c]quinolin-4-amines | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-06 | — | — | US | disclosed |
| EP-0389302-A1 | Olefinic 1H-imidazo [4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-09-26 | — | — | EP | disclosed |