Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 1.00 |
| ▸ | MMP9 | P14780 | 1/20 | 1.00 |
| ▸ | MMP8 | P22894 | 1/20 | 1.00 |
| ▸ | RAB9A | P51151 | 9/20 | 0.69 |
| ▸ | NPC1 | O15118 | 8/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | GAA | P10253 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | GLA | P06280 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.69 |
| ▸ | RELA | Q04206 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Phenylbenzo[D]Thiazole SCHEMBL12479300 | 0.96 | APP (0.93) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL13853339 | 0.92 | APP (1.00) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL29474819 | 0.90 | RAB9A (0.81) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL366824 | 0.90 | RAB9A (0.81) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL24295138 | 0.88 | RAB9A (0.79) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL4780914 | 0.88 | APP (0.77) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL754574 | 0.85 | RAB9A (0.73) | APPMMP9MMP8RAB9ANPC1 | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL94005 | 0.84 | RAB9A (0.75) | APPMMP9MMP8RAB9ANPC1 | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL30988131 | 0.84 | RAB9A (0.75) | APPMMP9MMP8RAB9ANPC1 | |
| SCHEMBL13067565 | 0.84 | APP (0.72) | APPMMP9MMP8RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119569722-A | Compound, preparation method and application of compound in treatment of Alzheimer's disease | 河南中医药大学 | 2025-03-07 | — | — | CN | claimed |
| CN-119462558-A | Bumetanide derivative and preparation method and application thereof | 河南中医药大学 | 2025-02-18 | — | — | CN | claimed |
| CN-118048155-A | Titanium nitride etching liquid, preparation method, application and cleaning method thereof | 浙江奥首材料科技有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-117777327-A | Manganese-based catalyst, preparation method and application | 铜仁学院 | 2024-03-29 | — | — | CN | claimed |
| CN-114225965-A | D-A covalent organic framework catalyst with diazosulfide structure and preparation method and application thereof | 中原工学院 | 2022-03-25 | — | — | CN | claimed |
| CN-109010847-B | Apoferritin-benzothiazole compound and preparation method and application thereof | 昆明理工大学 | 2021-07-16 | — | — | CN | claimed |
| CN-109010847-A | Apoferritin-benzothiazole compound compound and its preparation method and application | 昆明理工大学 | 2018-12-18 | — | — | CN | claimed |
| CN-107880034-A | A kind of fluorescence probe of Visual retrieval hydrazine based on benzothiazole and its production and use | 湖北理工学院 | 2018-04-06 | — | — | CN | claimed |
| CN-103450176-B | Naphthalimide compound containing 2- (4-aminophenyl) benzothiazole and application thereof | 大连理工大学 | 2016-07-06 | — | — | CN | claimed |
| US-9132115-B2 | Lipid raft, caveolin protein, and caveolar function modulation compounds and associated synthetic and therapeutic methods | KAY HEIDI (US) | 2015-09-15 | — | — | US | claimed |
| US-20050175554-A1 | Aminophenylbenzothiazole compounds | CIBA SPECIALTY CHEMICALS CORP. | 2005-08-11 | — | — | US | claimed |
| CN-1646507-A | Aminophenylbenzothiazole compounds | CIBA SC HOLDING AG (CH) | 2005-07-27 | — | — | CN | claimed |
| EP-1494641-A2 | AMINOPHENYLBENZOTHIAZOLE COMPOUNDS | Ciba SC Holding AG (CH) | 2005-01-12 | — | — | EP | claimed |
| WO-2003086341-A2 | AMINOPHENYLBENZOTHIAZOLE COMPOUNDS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-10-23 | — | — | WO | claimed |
| EP-0721336-B1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RES CAMPAIGN TECH (GB) | 1999-07-14 | — | — | EP | claimed |
| EP-0581245-B1 | Water-insoluble azo colouring agents | CLARIANT GMBH (DE) | 1998-12-23 | — | — | EP | claimed |
| EP-0721336-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-07-17 | — | — | EP | claimed |
| US-5428136-A | Water-insoluble azo colorants having two azo groups and a 1,4-bis (acetoacetylamino) benzene coupling component | HOECHST AG (DE) | 1995-06-27 | — | — | US | claimed |
| WO-1995006469-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-03-09 | — | — | WO | claimed |
| EP-0581245-A1 | Water-insoluble azo colouring agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-02-02 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050175554-A1 | Aminophenylbenzothiazole compounds | C5, C1S, C9 | APP 3487/4885MMP9 2202/4885MMP8 3957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.