SCHEMBL13067565

SCHEMBL13067565

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4nc5ccccc5s4)cc3)n2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ APP P05067 5/20 0.72
▸ MMP9 P14780 3/20 0.72
▸ MMP8 P22894 3/20 0.72
▸ RAB9A P51151 8/20 0.67
▸ NPC1 O15118 6/20 0.67
▸ KDM4E B2RXH2 5/20 0.67
▸ MAPT P10636 3/20 0.67
▸ LMNA P02545 3/20 0.67
▸ GLA P06280 2/20 0.67
▸ GAA P10253 2/20 0.67
▸ ALDH1A1 P00352 2/20 0.67
▸ PAX8 Q06710 1/20 0.66
▸ NOD2 Q9HC29 1/20 0.66
▸ L3MBTL1 Q9Y468 1/20 0.66
▸ SMN1; SMN2 Q16637 3/20 0.61
▸ MEN1 O00255 3/20 0.61
▸ KMT2A Q03164 3/20 0.61
▸ PKM P14618 1/20 0.61
▸ TNF P01375 1/20 0.61
▸ NOD1 Q9Y239 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24514780 1.00 APP (0.72) APPMMP9MMP8RAB9ANPC1
SCHEMBL23606715 0.92 APP (0.62) APPMMP9MMP8RAB9ANPC1
SCHEMBL24353063 0.92 RAB9A (0.61) APPMMP9MMP8RAB9ANPC1
SCHEMBL27049351 0.91 APP (0.60) APPMMP9MMP8RAB9ANPC1
SCHEMBL754574 0.91 RAB9A (0.73) APPMMP9MMP8RAB9ANPC1
2-Phenylbenzo[D]Thiazole SCHEMBL94005 0.91 RAB9A (0.75) APPMMP9MMP8RAB9ANPC1
2-Phenylbenzo[D]Thiazole SCHEMBL30988131 0.91 RAB9A (0.75) APPMMP9MMP8RAB9ANPC1
SCHEMBL25303434 0.90 RAB9A (0.59) APPMMP9MMP8RAB9ANPC1
SCHEMBL31208337 0.90 RAB9A (0.59) APPMMP9MMP8RAB9ANPC1
SCHEMBL25897016 0.90 RAB9A (0.59) APPMMP9MMP8RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 — — US disclosed
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-01-25 — — US disclosed
US-11316114-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same Rohm and Haas Erlectronic Materials Korea Ltd. 2022-04-26 — — US disclosed
WO-2016197353-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-15 — — WO disclosed
WO-2010126270-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME DOW ADVANCED DISPLAY MATERIALS,LTD. (KR) 2010-11-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240032418-A1 PLURALITY OF HOST MATERIALS, ORGANIC ELECTROLUMINESCENT COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, L3MBTL4, PIEZO1 APP 2789/4885MMP9 746/4885MMP8 3271/4885
US-11316114-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same EML4, ELAVL1, ELAVL3 APP 1426/4885MMP9 254/4885MMP8 1987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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