SCHEMBL8727434

SCHEMBL8727434

Fc1cc(Br)cc(F)c1/C(Cl)=C/Cl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8727439 1.00 DGAT1 (0.31) DGAT1
SCHEMBL7766225 0.78 DGAT1 (0.31) DGAT1
SCHEMBL7766231 0.78 DGAT1 (0.31) DGAT1
SCHEMBL1085223 0.73 DGAT1 (0.41) DGAT1
SCHEMBL7766058 0.71 DGAT1 (0.31) DGAT1
SCHEMBL17514744 0.67 DGAT1 (0.34) DGAT1
SCHEMBL25261067 0.67 ALDH1A1 (0.39) DGAT1
SCHEMBL7767226 0.67 DGAT1 (0.31) DGAT1
SCHEMBL7767224 0.67 DGAT1 (0.31) DGAT1
SCHEMBL22955911 0.65 DGAT1 (0.35) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5730901-A Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-24 US disclosed
EP-0742222-A2 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-11-13 EP disclosed