Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8731433 | 1.00 | LMNA (0.48) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL8731436 | 1.00 | LMNA (0.48) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL8727776 | 1.00 | LMNA (0.48) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL14618493 | 0.94 | LMNA (0.54) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL9477345 | 0.83 | ERN1 (0.40) | ERN1PTGS2IDO1AGXTHDAC2 | |
| SCHEMBL8730609 | 0.81 | ALDH1A1 (0.41) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL8731537 | 0.81 | ALDH1A1 (0.41) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL8730602 | 0.81 | ALDH1A1 (0.41) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL8731538 | 0.81 | ALDH1A1 (0.41) | LMNATP53CYP3A4TSHRKDM4E | |
| SCHEMBL198803 | 0.81 | ERN1 (0.47) | ERN1PTGS2MAOBIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882695-A1 | BENZYL ETHER DERIVATIVES, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY | CHISSO CORPORATION (JP) | 1998-12-09 | — | — | EP | disclosed |