⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23252274 | 0.82 | GABRA1 (0.32) | — | |
| SCHEMBL4101476 | 0.76 | GABRA1 (0.44) | — | |
| SCHEMBL8992392 | 0.76 | — | — | |
| SCHEMBL3974692 | 0.76 | TSHR (0.44) | — | |
| SCHEMBL5521697 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3640150 | 0.74 | TSHR (0.43) | — | |
| SCHEMBL12696836 | 0.73 | CYP2D6 (0.45) | — | |
| SCHEMBL1538924 | 0.73 | GABRA1 (0.35) | — | |
| SCHEMBL29549283 | 0.73 | HDAC8 (0.36) | — | |
| SCHEMBL28870 | 0.73 | HDAC8 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11376241-B2 | Aryl hydrocarbon receptor (AhR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2022-07-05 | — | — | US | disclosed |
| US-11376241-B2 | Aryl hydrocarbon receptor (AhR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2022-07-05 | — | — | US | disclosed |
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| EP-3577115-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-02 | — | — | EP | disclosed |
| EP-3577115-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-02 | — | — | EP | disclosed |
| US-20200031805-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-01-30 | — | — | US | disclosed |
| US-20200031805-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-01-30 | — | — | US | disclosed |
| CN-110325532-A | Aryl hydrocarbon receptor (AhR) adjusts immunomodulator compounds | 菲尼克斯药品股份公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110248940-A | Aryl hydrocarbon receptor (AhR) adjusts immunomodulator compounds | 菲尼克斯药品股份公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-110234650-A | Aryl hydrocarbon receptor (AhR) adjusts immunomodulator compounds | 菲尼克斯药品股份公司 | 2019-09-13 | — | — | CN | disclosed |
| WO-2018153893-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2018-08-30 | — | — | WO | disclosed |
| WO-2018141855-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2018-08-09 | — | — | WO | disclosed |
| WO-2018141857-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2018-08-09 | — | — | WO | disclosed |
| WO-2018141857-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2018-08-09 | — | — | WO | disclosed |
| US-5820785-A | ELECTROOPTIC SWITCHES; DISPLAYING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-10-13 | — | — | US | disclosed |