Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562862 | 0.75 | APP (0.55) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7413841 | 0.73 | APP (0.52) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10898918 | 0.72 | MAPT (0.62) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16439860 | 0.71 | APP (0.50) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28579920 | 0.68 | APP (0.46) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28600443 | 0.67 | APP (0.44) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29018689 | 0.67 | APP (0.44) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL840229 | 0.66 | APP (0.55) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2183993 | 0.66 | APP (0.55) | MAPTAPPCYP1A2CYP3A4CYP2C9 | |
| Butadiene SCHEMBL8867166 | 0.66 | APP (0.55) | MAPTAPPCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5820785-A | ELECTROOPTIC SWITCHES; DISPLAYING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-10-13 | — | — | US | claimed |
| US-5820785-A | ELECTROOPTIC SWITCHES; DISPLAYING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5820785-A | ELECTROOPTIC SWITCHES; DISPLAYING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-10-13 | — | — | US | disclosed |
| US-5820785-A | ELECTROOPTIC SWITCHES; DISPLAYING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-10-13 | — | — | US | disclosed |