Dimethylamine

Dimethylamine

SCHEMBL8728488

CNC.ClCc1cccc(Cl)c1Cl

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.56
TAAR1 Q96RJ0 2/20 0.50
IDO1 P14902 2/20 0.48
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
CYP2A13 Q16696 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CYP1A2 P05177 1/20 0.40
GLA P06280 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CARM1 Q86X55 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TSHR P16473 1/20 0.38
DBH P09172 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL283449 0.91 PNMT (0.65) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL21814337 0.89 PNMT (0.62) PNMTTAAR1IDO1KDM4EALDH1A1
Ammonia Solution, Strong SCHEMBL9576089 0.89 PNMT (0.62) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL3302008 0.79 PNMT (0.68) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL3001718 0.78 PNMT (0.56) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL29168328 0.75 TAAR1 (0.71) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL42704 0.75 PNMT (0.62) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL91279 0.75 PNMT (0.62) PNMTTAAR1IDO1KDM4EALDH1A1
SCHEMBL1539462 0.75 TAAR1 (0.44) PNMTTAAR1IDO1CYP1A2GLA
SCHEMBL11828147 0.73 PNMT (0.60) PNMTTAAR1IDO1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998047359-A1 RAPID AND LONG LASTING BIOCIDAL SYSTEM RHODIA LIMITED (GB) 1998-10-29 WO disclosed