Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2480109 | 0.78 | MEN1 (0.43) | ALDH1A1TSHRKMT2ATHRBTDP1 | |
| SCHEMBL24582819 | 0.77 | HPGD (0.45) | ALDH1A1TSHRERN1KMT2ATHRB | |
| SCHEMBL26704361 | 0.77 | EGFR (0.40) | ALDH1A1TSHRKMT2ATHRBTDP1 | |
| SCHEMBL17967051 | 0.76 | ERN1 (0.43) | ALDH1A1ERN1KMT2AMEN1NPC1 | |
| SCHEMBL14417384 | 0.74 | HPGD (0.56) | ALDH1A1TSHRKMT2ATHRBTDP1 | |
| SCHEMBL2557469 | 0.74 | HPGD (0.61) | ALDH1A1ERN1KMT2ATDP1MEN1 | |
| SCHEMBL249552 | 0.72 | KMT2A (0.71) | ALDH1A1TSHRERN1KMT2ATHRB | |
| SCHEMBL31175932 | 0.72 | KMT2A (0.71) | ALDH1A1TSHRERN1KMT2ATHRB | |
| SCHEMBL13472040 | 0.72 | ADRA1A (0.40) | ALDH1A1KMT2ATHRBTDP1MEN1 | |
| SCHEMBL5723230 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRERN1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |