Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8198510 | 0.96 | PTGES (0.51) | PTGESALOX5PPARGBCHE | |
| SCHEMBL8198059 | 0.92 | PTGES (0.51) | PTGESALOX5PPARGSIGMAR1BCHE | |
| SCHEMBL9077677 | 0.90 | BCHE (0.55) | BCHE | |
| SCHEMBL9074720 | 0.87 | SIGMAR1 (0.50) | PTGESALOX5PPARGSIGMAR1 | |
| SCHEMBL8202702 | 0.87 | PTGES (0.47) | PTGESALOX5PPARGSIGMAR1 | |
| SCHEMBL8198003 | 0.83 | SIGMAR1 (0.52) | PTGESALOX5PPARGSIGMAR1 | |
| SCHEMBL8189465 | 0.81 | SIGMAR1 (0.52) | PTGESALOX5PPARGSIGMAR1 | |
| SCHEMBL8728742 | 0.81 | SIGMAR1 (0.74) | SIGMAR1 | |
| SCHEMBL8201210 | 0.81 | SIGMAR1 (0.67) | PTGESALOX5PPARGSIGMAR1 | |
| SCHEMBL9077324 | 0.79 | SIGMAR1 (0.42) | PTGESALOX5PPARGSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641766-B1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-11-11 | — | — | EP | claimed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | claimed |
| EP-0641766-B1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1998-11-11 | — | — | EP | disclosed |
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |