Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795201 | 0.94 | GAA (0.45) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL2347168 | 0.87 | ALDH1A1 (0.43) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL11385199 | 0.87 | ALDH1A1 (0.43) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL11446428 | 0.84 | ALDH1A1 (0.41) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL8459792 | 0.83 | ALDH1A1 (0.44) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL643099 | 0.82 | ALDH1A1 (0.42) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL9009542 | 0.82 | TYR (0.40) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL18725939 | 0.80 | ALDH1A1 (0.40) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL6956315 | 0.78 | PRMT5 (0.47) | ALDH1A1GAAPKMMEN1KMT2A | |
| SCHEMBL9813093 | 0.77 | ALDH1A1 (0.36) | ALDH1A1GAAPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619590-A2 | COMPOUNDS FOR DIAGNOSING NEURODEGENERATIVE DISEASES AT THE RETINA | Technische Universität Darmstadt (DE) | 2013-07-31 | — | — | EP | disclosed |
| EP-2619591-A2 | COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM | Technische Universität Darmstadt (DE) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012041292-A2 | COMPOUNDS FOR DIAGNOSING NEURODEGENERATIVE DISEASES AT THE RETINA | KLINIKUM DARMSTADT GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012037928-A2 | COMPOUNDS FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISORDERS ON THE OLFACTORY EPITHELIUM | KLINIKUM DARMSTADT GMBH (DE) | 2012-03-29 | — | — | WO | disclosed |