Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813110 | 0.90 | MEN1 (0.37) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL11385199 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL2347168 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL8795201 | 0.83 | GAA (0.45) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL11334473 | 0.80 | ESR2 (0.45) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL8459792 | 0.79 | ALDH1A1 (0.44) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL3907809 | 0.79 | ALDH1A1 (0.45) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL872880 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL11446428 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAPKMLMNASMN1; SMN2 | |
| SCHEMBL9340848 | 0.75 | ALDH1A1 (0.52) | ALDH1A1PKMLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0304780-B1 | PROCESS FOR LABELLING SUBSTANCES WITH TECHNETIUM OR RHENIUM | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-07 | — | — | EP | disclosed |