SCHEMBL8728904

SCHEMBL8728904

C=C(c1ccccc1)c1ccc(CCCCc2ccc(C(=C)c3ccccc3)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.50
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAOB P27338 2/20 0.48
HDAC8 Q9BY41 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
IGF1R P08069 1/20 0.47
ALOX15 P16050 1/20 0.47
MAOA P21397 1/20 0.45
DPP4 P27487 1/20 0.44
MAPT P10636 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
HTR2A P28223 1/20 0.43
THRA P10827 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3116481 0.92 HDAC1 (0.45) HDAC1MEN1KMT2AMAOBHDAC8
SCHEMBL8733948 0.91 MEN1 (0.52) HDAC1MEN1KMT2AMAOBHDAC8
SCHEMBL10602808 0.91 THRA (0.57) MEN1KMT2AMAPTTHRATHRB
SCHEMBL9806373 0.89 HDAC1 (0.52) HDAC1MEN1KMT2AMAOBHDAC8
SCHEMBL6546856 0.88 TRPV1 (0.55) MEN1KMT2AMAPTTHRATHRB
SCHEMBL537537 0.88 TDP1 (0.43) HDAC1MEN1KMT2AMAOBHDAC8
SCHEMBL17444461 0.84 MEN1 (0.43) HDAC1MEN1KMT2AMAOBHDAC8
SCHEMBL17453269 0.84 MEN1 (0.43) HDAC1MEN1KMT2AHDAC8NPC1
SCHEMBL17453272 0.84 MEN1 (0.43) HDAC1MEN1KMT2AMAOBHDAC8
SCHEMBL23102019 0.83 TAAR1 (0.58) MEN1KMT2AMAOBTDP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0678526-B1 Ethylene polymers having both ends modified and processes for the production thereof TONEN CORP (JP) 1998-04-01 EP claimed
EP-0678526-A2 Ethylene polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1995-10-25 EP claimed
EP-0530408-A1 Olefin polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1993-03-10 EP claimed
EP-0678526-B1 Ethylene polymers having both ends modified and processes for the production thereof TONEN CORP (JP) 1998-04-01 EP disclosed
EP-0227124-B2 Olefinic benzocyclobutene polymers and processes for the preparation thereof SHELL INT RESEARCH (NL) 1996-01-31 EP disclosed
EP-0678526-A2 Ethylene polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1995-10-25 EP disclosed
EP-0532804-B1 An ethylene polymer and a process for its production TONEN CORP (JP) 1995-06-28 EP disclosed
US-5367033-A Hydroxy or carboxy endcapped polyethylene reacted with diol or diacid TONEN CORPORATION (JP) 1994-11-22 US disclosed
US-5334678-A Using a coordination catalyst containing a vanadium chelate compound and a dialkylaluminum halide TONEN CORPORATION (JP) 1994-08-02 US disclosed
EP-0532804-A1 An ethylene polymer and a process for its production Tonen Corporation (JP) 1993-03-24 EP disclosed
EP-0530408-A1 Olefin polymers having both ends modified and processes for the production thereof Tonen Corporation (JP) 1993-03-10 EP disclosed
US-4722974-A POLYMERIZED WITH UNSATURATED AROMATIC HYDROCARBON AND CONJUGATED DIENES; CROSSLINKABLE; SOLVENT RESISTANT SHELL OIL COMPANY (US) 1988-02-02 US disclosed
US-4687815-A Hydrogenated block copolymers SHELL OIL COMPANY (US) 1987-08-18 US disclosed