Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3116481 | 0.96 | HDAC1 (0.45) | TDP1KMT2ACES2CES1MEN1 | |
| SCHEMBL8728904 | 0.88 | HDAC1 (0.50) | TDP1KMT2AMEN1HDAC8NPC1 | |
| SCHEMBL8733948 | 0.84 | MEN1 (0.52) | TDP1KMT2ACES2CES1MEN1 | |
| SCHEMBL9806373 | 0.82 | HDAC1 (0.52) | TDP1KMT2AMEN1HDAC8NPC1 | |
| SCHEMBL6546856 | 0.81 | TRPV1 (0.55) | KMT2AMEN1THRATHRBTRPV1 | |
| SCHEMBL9125569 | 0.81 | ALDH1A1 (0.52) | TDP1KMT2ACES2CES1MEN1 | |
| SCHEMBL8983371 | 0.80 | CES2 (0.64) | TDP1KMT2ACES2CES1MEN1 | |
| SCHEMBL10602808 | 0.80 | THRA (0.57) | KMT2AMEN1THRATHRBTRPV1 | |
| SCHEMBL17183156 | 0.78 | HDAC1 (0.53) | TDP1KMT2ACES2CES1MEN1 | |
| Ethylene SCHEMBL28160202 | 0.78 | TDP1 (0.64) | TDP1HDAC8HDAC1HDAC3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099831-B1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | UNIV AKRON (US) | 2019-07-31 | — | — | EP | disclosed |
| US-10005852-B2 | Polyisobutylenes and process for making same | THE UNIVERSITY OF AKRON (US) | 2018-06-26 | — | — | US | disclosed |
| US-20180066079-A1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2018-03-08 | — | — | US | disclosed |
| US-9834622-B2 | Polyisobutylenes and process for making same | THE UNIVERSITY OF AKRON (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170174796-A1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | UNIV AKRON (US) | 2017-06-22 | — | — | US | disclosed |
| EP-2414432-B1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-9587067-B2 | Polyisobutylenes and process for making same | THE UNIVERSITY OF AKRON (US) | 2017-03-07 | — | — | US | disclosed |
| US-9359465-B2 | Polyisobutylenes and process for making same | THE UNIVERSITY OF AKRON (US) | 2016-06-07 | — | — | US | disclosed |
| US-9315595-B2 | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE COMPANY LLC (US) | 2016-04-19 | — | — | US | disclosed |
| US-20160090437-A1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2016-03-31 | — | — | US | disclosed |
| CN-102356114-A | Amine-terminated telechelic polymers and precursors thereto and methods for their preparation | CHEVRON ORONITE CO | 2012-02-15 | — | — | CN | disclosed |
| EP-2414432-A2 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | Chevron Oronite Company LLC (US) | 2012-02-08 | — | — | EP | disclosed |
| US-20110213084-A1 | POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2011-09-01 | — | — | US | disclosed |
| EP-2344555-A1 | POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME | The University of Akron (US) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010117619-A2 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | CHEVRON ORONITE COMPANY LLC (US) | 2010-10-14 | — | — | WO | disclosed |
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | UNIVERSITY OF SOUTHERN MISSISSIPPI | 2010-09-30 | — | — | US | disclosed |
| US-20100130696-A1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2010-05-27 | — | — | US | disclosed |
| WO-2010039986-A1 | POLYMERS HAVING BOTH HARD AND SOFT SEGMENTS, AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2010-04-08 | — | — | WO | disclosed |
| EP-2099831-A1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008066914-A1 | POLYISOBUTYLENES AND PROCESS FOR MAKING SAME | THE UNIVERSITY OF AKRON (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249001-A1 | AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION | TERT, TELO2, TSPO | TDP1 451/4885KMT2A 1040/4885CES2 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.