Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8730920 | 0.74 | BCHE (0.30) | BCHEACHE | |
| SCHEMBL22184064 | 0.73 | ACHE (1.00) | BCHEACHEKMT2AMEN1MAPT | |
| SCHEMBL797923 | 0.71 | BCHE (0.34) | BCHEACHE | |
| SCHEMBL7633118 | 0.69 | BCHE (0.32) | BCHEACHECYP3A4CYP2D6TSHR | |
| SCHEMBL6344924 | 0.69 | DRD2 (0.38) | KDM4ECYP3A4CYP2D6LMNAHTR2C | |
| SCHEMBL27372929 | 0.69 | CYP11B1 (0.33) | KDM4ECYP3A4CYP2D6LMNAHTR2C | |
| SCHEMBL5859366 | 0.69 | CYP11B1 (0.33) | KDM4ECYP3A4CYP2D6LMNAHTR2C | |
| SCHEMBL3259666 | 0.68 | BCHE (0.89) | BCHEACHEKMT2AMEN1HTR2C | |
| SCHEMBL796720 | 0.68 | BCHE (0.31) | BCHEACHE | |
| SCHEMBL1453657 | 0.67 | HTR2A (0.40) | KMT2AMEN1KDM4ECYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839833-A2 | Catalyst systems for the polymerization and copolymerization of alpha-olefins | REPSOL QUIMICA S.A. (ES) | 1998-05-06 | — | — | EP | disclosed |