SCHEMBL8729043

SCHEMBL8729043

NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 14/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
DPP7 Q9UHL4 1/20 0.44
GHSR Q92847 1/20 0.44
FOLH1 Q04609 1/20 0.43
SLC15A2 Q16348 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29381549 1.00 CPB2 (0.46) CPB2MEN1KMT2ADPP7GHSR
Bromide SCHEMBL8990122 0.99 CPB2 (0.45) CPB2MEN1KMT2ADPP7GHSR
Bromide SCHEMBL8990118 0.99 CPB2 (0.45) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL29630532 0.95 NMT1 (0.45) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL23303426 0.95 MEN1 (0.48) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL29578895 0.95 MEN1 (0.48) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL29470578 0.95 MEN1 (0.48) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL23303428 0.95 MEN1 (0.48) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL18075734 0.95 MEN1 (0.48) CPB2MEN1KMT2ADPP7GHSR
SCHEMBL14906323 0.95 MEN1 (0.48) CPB2MEN1KMT2ADPP7GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0708637-A4 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS UNIV CALIFORNIA (US) 1998-08-12 EP disclosed
EP-0708637-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-05-01 EP disclosed
WO-1995002397-A1 SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM COMPRISING DENDRIMER POLYCATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-01-26 WO disclosed