SCHEMBL8729101

SCHEMBL8729101

Cc1cc2cc(O)c(O)cc2[nH]1.Cn1ccc2cc(O)c(O)cc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.37
PRKCI P41743 1/20 0.37
KEAP1 Q14145 1/20 0.37
GPR35 Q9HC97 2/20 0.36
AXL P30530 1/20 0.35
PIK3CB P42338 1/20 0.34
DAO P14920 2/20 0.33
DDO Q99489 1/20 0.33
ACHE P22303 1/20 0.33
HSP90AA1 P07900 2/20 0.32
HSP90AB1 P08238 2/20 0.32
HSP90B1 P14625 1/20 0.32
TRAP1 Q12931 1/20 0.32
HSD11B1 P28845 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL108453 0.82 PRKCI (0.50) CYP2A6PRKCIGPR35PIK3CBDAO
SCHEMBL29803376 0.82 PRKCI (0.50) CYP2A6PRKCIGPR35PIK3CBDAO
Bromide SCHEMBL4625069 0.80 PRKCI (0.48) CYP2A6PRKCIGPR35PIK3CBDAO
Hydrochloric Acid SCHEMBL4624814 0.80 PRKCI (0.48) CYP2A6PRKCIGPR35PIK3CBDAO
SCHEMBL8729103 0.80 GPR35 (0.50) CYP2A6KEAP1GPR35AXLDAO
SCHEMBL366714 0.80 GPR35 (0.50) CYP2A6KEAP1GPR35AXLDAO
SCHEMBL29638854 0.80 GPR35 (0.50) CYP2A6KEAP1GPR35AXLDAO
Bromide SCHEMBL8431246 0.78 GPR35 (0.48) CYP2A6KEAP1GPR35AXLDAO
Bromide SCHEMBL9788685 0.76 GPR35 (0.47) CYP2A6KEAP1GPR35AXLDAO
SCHEMBL18683804 0.72 PRKCI (0.60) CYP2A6PRKCIPIK3CBHSD11B1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776241-A MELANIN PIGMENT PARTICLES FOR COSMETICS L'OREAL (FR) 1998-07-07 US disclosed