SCHEMBL108453

SCHEMBL108453

Cn1ccc2cc(O)c(O)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.50
CYP2A6 P11509 2/20 0.46
PIK3CB P42338 1/20 0.46
GPR35 Q9HC97 1/20 0.41
DAO P14920 1/20 0.41
ACHE P22303 3/20 0.39
HSD11B1 P28845 1/20 0.38
TUBB4A P04350 1/20 0.37
TUBB P07437 1/20 0.37
TUBA3C P0DPH7 1/20 0.37
TUBA1B P68363 1/20 0.37
TUBA4A P68366 1/20 0.37
TUBB4B P68371 1/20 0.37
TUBB3 Q13509 1/20 0.37
TUBB2A Q13885 1/20 0.37
TUBB8 Q3ZCM7 1/20 0.37
TUBA3E Q6PEY2 1/20 0.37
TUBA1A Q71U36 1/20 0.37
TUBA1C Q9BQE3 1/20 0.37
TUBB6 Q9BUF5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29803376 1.00 PRKCI (0.50) PRKCICYP2A6PIK3CBGPR35DAO
Hydrochloric Acid SCHEMBL4624814 0.98 PRKCI (0.48) PRKCICYP2A6PIK3CBGPR35DAO
Bromide SCHEMBL4625069 0.98 PRKCI (0.48) PRKCICYP2A6PIK3CBGPR35DAO
SCHEMBL29573918 0.84 PRKCI (0.44) PRKCICYP2A6PIK3CBMAOBAPP
SCHEMBL18683804 0.83 PRKCI (0.60) PRKCICYP2A6PIK3CBHSD11B1TUBB4A
SCHEMBL3186062 0.82 PRKCI (0.43) PRKCICYP2A6PIK3CBDAOACHE
SCHEMBL3194274 0.82 PRKCI (0.43) PRKCICYP2A6PIK3CBDAOHSD11B1
SCHEMBL8729101 0.82 CYP2A6 (0.37) PRKCICYP2A6PIK3CBGPR35DAO
SCHEMBL8053219 0.81 TUBB4A (0.48) PRKCIACHETUBB4ATUBBTUBA3C
SCHEMBL25879930 0.81 HSP90AB1 (0.48) PRKCI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR DR. KURT WOLFF GMBH & CO. KG (DE) 2026-04-09 US claimed
EP-4154864-B1 REPIGMENTING COMPOSITION FOR KERATIN FIBRES, ESPECIALLY HUMAN HAIR DR KURT WOLFF GMBH & CO KG (DE) 2025-12-17 EP claimed
EP-4450054-A2 REPIGMENTING COMPOSITION FOR KERATIN FIBRES, ESPECIALLY HUMAN HAIR Dr. Kurt Wolff GmbH & Co. KG (DE) 2024-10-23 EP claimed
WO-2024205052-A1 COMPOSITION FOR COLORING HAIR 주식회사 엘지생활건강 2024-10-03 WO claimed
WO-2024062091-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR DR. KURT WOLFF GMBH & CO. KG (DE) 2024-03-28 WO claimed
EP-4154864-A1 REPIGMENTING COMPOSITION FOR KERATIN FIBRES, ESPECIALLY HUMAN HAIR Dr. Kurt Wolff GmbH & Co. KG (DE) 2023-03-29 EP claimed
WO-2021018445-A1 OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR HENKEL AG & CO. KGAA (DE) 2021-02-04 WO claimed
US-10292921-B2 Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms L'OREAL (FR) 2019-05-21 US claimed
US-20180092822-A1 HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS L'OREAL (FR) 2018-04-05 US claimed
EP-2582351-B1 HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT L'ORÉAL (FR) 2017-08-02 EP claimed
EP-0335477-B1 THE USE OF N-SUBSTITUTED-5,6-DIHYDROXYINDOLES AS A HAIR COLORING AGENT Bristol-Myers Squibb Company (US) 1993-07-21 EP claimed
US-5205837-A Formed in situ by oxidation of indole compound L'OREAL (FR) 1993-04-27 US claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
EP-0337853-B1 PROCEDURE OF THE PREVERSATION OF THE DYEING ABILITY OF 5,6-DIHYDROXY-INDOLE AND ITS DERIVATIVES IN AN AQUEOUS MILIEU, COMPOSITION AND PROCEDURE OF DYEING L'OREAL (FR) 1992-05-20 EP claimed
US-4968497-A Skin tanning composition and method CLAIROL INCORPORATED (US) 1990-11-06 US claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 EP claimed
US-4932977-A Indole-aldehyde hair dyes CLAIROL INCORPORATED (US) 1990-06-12 US claimed
EP-0356119-A1 Skin tanning composition and method Bristol-Myers Company (US) 1990-02-28 EP claimed
EP-0337853-A1 Procedure of the preversation of the dyeing ability of 5,6-dihydroxy-indole and its derivatives in an aqueous milieu, composition and procedure of dyeing L'OREAL (FR) 1989-10-18 EP claimed
EP-0335477-A2 The use of N-substituted-5,6-dihydroxyindoles as a hair coloring agent Bristol-Myers Squibb Company (US) 1989-10-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260096976-A1 AGENT FOR REPIGMENTATION OF KERATIN FIBERS, IN PARTICULAR HUMAN HAIR TYR, KRT18, TPH1 PRKCI 1887/4885CYP2A6 285/4885PIK3CB 4379/4885
US-20180092822-A1 HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOL(IN)E COMPOUND AND A POLYCYCLIC AROMATIC COMPOUND CONTAINING AT LEAST TEN CARBON ATOMS KRT18, TYR, INCENP PRKCI 457/4885CYP2A6 1579/4885PIK3CB 822/4885
US-10292921-B2 Hair dyeing process using a composition comprising at least one indol(in)e compound and a polycyclic aromatic compound containing at least ten carbon atoms KRT18, TYR, INCENP PRKCI 397/4885CYP2A6 1599/4885PIK3CB 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.