Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8727525 | 1.00 | LMNA (0.37) | LMNASLC6A1SLC6A11ATML3MBTL1 | |
| SCHEMBL8343421 | 0.81 | LMNA (0.40) | LMNASLC6A1SLC6A11ATML3MBTL1 | |
| SCHEMBL6854308 | 0.74 | MDM4 (0.37) | CHRM3 | |
| SCHEMBL1793271 | 0.73 | CHRM2 (0.36) | LMNAATML3MBTL1CHRM2CHRM3 | |
| SCHEMBL6853795 | 0.72 | LMNA (0.39) | LMNASLC6A1SLC6A11 | |
| SCHEMBL8729183 | 0.72 | LMNA (0.39) | LMNASLC6A1SLC6A11 | |
| SCHEMBL8729229 | 0.72 | LMNA (0.39) | LMNASLC6A1SLC6A11 | |
| SCHEMBL8346731 | 0.70 | ATM (0.41) | SLC6A1SLC6A11ATML3MBTL1CHRM2 | |
| SCHEMBL8661016 | 0.69 | MAPT (0.41) | L3MBTL1CHRM2CHRM3 | |
| SCHEMBL28385294 | 0.69 | LMNA (0.38) | LMNAATML3MBTL1CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |