Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1792702 | 0.82 | PTGIR (0.31) | CHRM3 | |
| SCHEMBL8729145 | 0.73 | LMNA (0.37) | CHRM2CHRM3LMNAATML3MBTL1 | |
| SCHEMBL8727525 | 0.73 | LMNA (0.37) | CHRM2CHRM3LMNAATML3MBTL1 | |
| SCHEMBL12613814 | 0.69 | SLC6A11 (0.47) | MEN1KMT2AKCNH2CYP3A4 | |
| SCHEMBL8343421 | 0.69 | LMNA (0.40) | CHRM2CHRM3CHRM1CYP2D6HRH1 | |
| SCHEMBL8346731 | 0.69 | ATM (0.41) | CHRM2CHRM3CHRM1CYP2D6ATM | |
| SCHEMBL6855483 | 0.65 | KDM4E (0.31) | CYP2D6 | |
| SCHEMBL6801407 | 0.65 | KDM4E (0.31) | CYP2D6 | |
| Ethylene Glycol SCHEMBL11275979 | 0.64 | KIF11 (0.45) | KCNH2CYP3A4CYP2C9ALDH1A1TSHR | |
| Biphenyl SCHEMBL28424673 | 0.64 | CYP2D6 (0.49) | CYP2D6MEN1KMT2AESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2011-10-06 | — | — | US | disclosed |
| US-7951926-B2 | Method for the synthesis of oligonucleotide derivatives | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-05-31 | — | — | US | disclosed |
| EP-2021351-A2 | METHOD FOR THE SYNTHESIS OF TRIAZOLE-CONTAINING OLIGONUCLEOTIDE DERIVATIVES | Centre National de la Recherche Scientifique (FR) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007125429-A2 | METHOD FOR THE SYNTHESIS OF TRIAZOLE- CONTAINING OLIGONUCLEOTIDE DERIVATIVES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2007-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245478-A1 | Method for the Synthesis of Oligonucleotide Derivatives | MSN, RNGTT, DCLRE1B | CHRM2 4570/4885CHRM3 3251/4885CHRM1 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.