SCHEMBL8729210

SCHEMBL8729210

CCOC(=O)C1=CC2=CCC(O)=CC2=N1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.35
CA1 P00915 6/20 0.35
CA2 P00918 6/20 0.35
CA7 P43166 6/20 0.35
CA9 Q16790 6/20 0.35
CA14 Q9ULX7 6/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
NR1H2 P55055 1/20 0.34
NR1H3 Q13133 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TSHR P16473 1/20 0.33
FGB P02675 1/20 0.33
PDE4D Q08499 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10132606 0.67 CYP1A2 (0.44) CYP1A2TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL13743229 0.67 CYP1A2 (0.41) CA12CA1CA2CA7CA9
SCHEMBL678155 0.66 CYP1A2 (0.40) CA12CA1CA2CA7CA9
SCHEMBL30489156 0.64 ALDH1A1 (0.36) CYP1A2CYP2C9CYP2C19TSHRPDE4D
SCHEMBL1662475 0.62 CYP1A2 (0.42) CA12CA1CA2CA7CA9
SCHEMBL4915482 0.62 CYP1A2 (0.42) CA12CA1CA2CA7CA9
SCHEMBL10447298 0.61 TSHR (0.48) CA12CA1CA2CA7CA9
SCHEMBL3648754 0.61 MAPT (0.35) CA12CA1CA2CA7CA9
SCHEMBL29709832 0.61 LMNA (0.38) CA12CA1CA2CA7CA9
SCHEMBL10253085 0.60 ALDH1A1 (0.41) TSHRNPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5776241-A MELANIN PIGMENT PARTICLES FOR COSMETICS L'OREAL (FR) 1998-07-07 US disclosed