Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.53 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826468 | 0.88 | MRGPRX4 (0.53) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL30180651 | 0.86 | MRGPRX4 (0.52) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL1339773 | 0.86 | MRGPRX4 (0.52) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL644216 | 0.82 | SMN1; SMN2 (0.58) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL31442462 | 0.82 | SMN1; SMN2 (0.58) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10774877 | 0.82 | NR4A2 (0.61) | MRGPRX4CYSLTR1RAB9ANPC1KMT2A | |
| SCHEMBL18401495 | 0.81 | MRGPRX4 (0.48) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL16167223 | 0.81 | GRM5 (0.51) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4978207 | 0.81 | MAPT (0.54) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL6003898 | 0.81 | MRGPRX4 (0.56) | MRGPRX4CYSLTR1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998043649-A2 | AGE PRODUCTION INHIBITORY COMPOSITION COMPRISING A MAILLARD REACTION INHIBITOR AND VITAMIN B¿6? | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-08 | — | — | WO | disclosed |
| US-5422360-A | Hydrazonoimidazolidin-4-one derivatives; treatment of diabetes and aging disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-06-06 | — | — | US | disclosed |
| EP-0531812-A1 | Maillard reaction inhibitor, process for producing it, composition containing it and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-17 | — | — | EP | disclosed |