Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757882 | 0.87 | ACACB (0.47) | ACACBHSD17B10HDAC8TSHRSMN1; SMN2 | |
| SCHEMBL8765787 | 0.85 | POLB (0.50) | POLBGAANPSR1ALDH1A1ADRB3 | |
| SCHEMBL6106293 | 0.81 | POLB (0.47) | POLBGAANPSR1ALDH1A1ADRB3 | |
| SCHEMBL7283668 | 0.80 | ACACB (0.49) | ACACBGAAALDH1A1HIF1AKDM4E | |
| SCHEMBL8728457 | 0.80 | ACACB (0.50) | ACACBHIF1AHDAC8 | |
| SCHEMBL9443694 | 0.79 | ADRB3 (0.51) | POLBGAANPSR1ALDH1A1ADRB3 | |
| SCHEMBL9443665 | 0.79 | ADRB3 (0.51) | POLBGAANPSR1ALDH1A1ADRB3 | |
| SCHEMBL9443701 | 0.79 | ADRB3 (0.51) | POLBGAANPSR1ALDH1A1ADRB3 | |
| SCHEMBL9688635 | 0.79 | ALOX15 (0.49) | ACACBADRB3HSD17B10HDAC8TSHR | |
| SCHEMBL9688057 | 0.79 | ALOX15 (0.49) | ACACBADRB3HSD17B10HDAC8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750524-A | ADMINISTERING AN SULFAMIDE SUBSTITUTED INDAN DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-12 | — | — | US | disclosed |