Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 6/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688045 | 1.00 | ALOX15 (0.49) | ALOX15TSHRHSD17B10DRD2ACACB | |
| SCHEMBL9688057 | 1.00 | ALOX15 (0.49) | ALOX15TSHRHSD17B10DRD2ACACB | |
| SCHEMBL8757882 | 0.91 | ACACB (0.47) | ALOX15TSHRHSD17B10DRD2ACACB | |
| SCHEMBL9365135 | 0.86 | ALOX15 (0.52) | ALOX15TSHRHSD17B10ADRB3ADRB1 | |
| SCHEMBL9132962 | 0.84 | DRD2 (0.53) | DRD2ACACBACACA | |
| SCHEMBL5681677 | 0.83 | MTNR1A (0.53) | ALOX15TSHRHSD17B10DRD2ADRB3 | |
| SCHEMBL7035289 | 0.83 | MTNR1A (0.53) | ALOX15TSHRHSD17B10DRD2ADRB3 | |
| SCHEMBL9361441 | 0.82 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9133081 | 0.82 | DRD2 (0.50) | DRD2ACACBACACA | |
| SCHEMBL9362314 | 0.82 | DRD2 (0.50) | DRD2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130339-A | Intestine and uterine motility modulators for reduction of intraocular pressure for glaucoma treatment | SANOFI (FR) | 1992-07-14 | — | — | US | disclosed |