Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724364 | 0.94 | MAPT (0.47) | MAPTSMN1; SMN2THRBTP53RAB9A | |
| SCHEMBL8728075 | 0.92 | MAPT (0.45) | MAPTSMN1; SMN2THRBTP53RAB9A | |
| SCHEMBL8077449 | 0.90 | MAPT (0.43) | MAPTSMN1; SMN2THRBTP53RAB9A | |
| SCHEMBL8067467 | 0.89 | MAPT (0.39) | MAPTSMN1; SMN2THRBTP53RAB9A | |
| SCHEMBL8077421 | 0.87 | SMN1; SMN2 (0.48) | MAPTSMN1; SMN2THRBTP53RAB9A | |
| SCHEMBL8729280 | 0.87 | TNFRSF1A (0.41) | MAPTSMN1; SMN2RAB9ANPC1TNFRSF1A | |
| SCHEMBL8077314 | 0.83 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBL3MBTL1 | |
| SCHEMBL8077327 | 0.83 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBL3MBTL1 | |
| SCHEMBL8081986 | 0.83 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBL3MBTL1 | |
| SCHEMBL8080490 | 0.83 | ALDH1A1 (0.46) | MAPTSMN1; SMN2THRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5800733-A | Photo cross-linkable liquid crystal derivatives | ROLIC AG (CH) | 1998-09-01 | — | — | US | disclosed |